Uva ursi is one of my favorite remedies for urinary tract infections. This is due to a substance called arbutin. When ingested, it is transformed into a compound called hydroquinone as it passes through the kidneys. Hydroquinone is a powerful disinfectant. It works best when the urine is alkaline, which is in contrast to cranberry juice, which works better with acid urine.
The presence of arbutin is not confined to uva ursi, however, various species of manzanitas also contain arbutin, as does pipsissewa, another member of the same family. So, it is likely you could harvest the leaves of various species and also use them for urinary tract infections.
I’ve personally found uva ursi a very dependable remedy for UTIs, but I think it works best as a tea. If you make an infusion you get less tannin, so it’s not so astringent, but you do get the arbutin. I have used the tincture, too, both for UTIs and also for urinary incontinence, because the tannins do help to tone the bladder sphincter.
Uva ursi is an irritating diuretic and should be avoided when there is acute kidney inflammation. If in doubt, it may be wise to combine it with soothing, non-irritating diuretics like horsetail, cornsilk, and marshmallow.