The main thing I’ve used pau d’arco for is to treat fungal or yeast infections. I’ve seen some people get very good results from using it, especially in a tea form. And, because it is a bark, decocted teas work the best.
To make a decoction of pau d'arco bring one quart of water to a boil, add one heaping teaspoon of the bark pieces, reduce the heat, and simmer on low for 20-30 minutes. Drink two to four cups per day, drinking some of the tea every four hours or so. I’m not a big tea fan, but I think pau d’arco tea tastes pretty good.
I’ve seen this help women with vaginal yeast infections and people who suffer from intestinal dysbiosis, which we used to think of as systemic Candidiasis, or yeast overgrowth, but I think is more correctly thought of as a poor balance of intestinal microbes. The symptoms include gas and bloating, cravings for sugar, brain fog, fatigue, and sinus congestion. I think that like black walnut, it probably also helps to tone up leaky gut.
Of course, all this works best in conjunction with some dietary changes. Stop eating all simple sugars and refined carbohydrates like white flour and white rice. Eat some fermented vegetables and/or take probiotic supplements, too.